In Pursuit of Memory
Alzheimer's is the great global epidemic of our time, affecting millions worldwide -- there are more than 5 million people diagnosed in the US alone. And as our population ages, scientists are working against the clock to find a cure.Neuroscientist Joseph Jebelli is among them. His beloved grandfather had Alzheimer's and now he's written the book he needed then -- a very human history of this frightening disease. But In Pursuit of Memory is also a thrilling scientific detective story that takes you behind the headlines. Jebelli's quest takes us from nineteenth-century Germany and post-war England, to the jungles of Papua New Guinea and the technological proving grounds of Japan; through America, India, China, Iceland, Sweden, and Colombia. Its heroes are scientists from around the world -- many of whom he's worked with -- and the brave patients and families who have changed the way that researchers think about the disease.This compelling insider's account shows vividly why Jebelli feels so hopeful about a cure, but also why our best defense in the meantime is to understand the disease. In Pursuit of Memory is a clever, moving, eye-opening guide to the threat one in three of us faces now.

In Pursuit of Memory Details

TitleIn Pursuit of Memory
Author
LanguageEnglish
ReleaseOct 31st, 2017
PublisherLittle, Brown and Company
ISBN-139780316360791
Rating
GenreNonfiction, Science, Health, Medical

In Pursuit of Memory Review

  • Paul
    January 1, 1970
    When you think of diseases that kill people cancer and heart disease would most top peoples list, but with the population in the western world getting older, other illnesses are having an effect on mortality rates and people’s quality of life. One of the most significant is Alzheimer's and dementia, a cruel disease that leaves the shell of the person whilst stealing their personality, dignity and their memories. The first time that Joseph Jebelli came across this illness was when he was twelve y When you think of diseases that kill people cancer and heart disease would most top peoples list, but with the population in the western world getting older, other illnesses are having an effect on mortality rates and people’s quality of life. One of the most significant is Alzheimer's and dementia, a cruel disease that leaves the shell of the person whilst stealing their personality, dignity and their memories. The first time that Joseph Jebelli came across this illness was when he was twelve years old and his grandfather started doing strange things and becoming ‘indefinably peculiar’; Gone was the warm person he had known. This family tragedy became a pivotal point in his life and drove him to pursue a career in science researching the very disease that claimed his grandfather.I felt totally alone, with the world receding away from me in every direction, and you could have used my anger to weld steel – Sir Terry PratchettJebelli is now an established expert in the field of Alzheimer's research and in this interesting and informative book he sets about describing the background with Alois Alzheimer's discovery of the illness in 1906 all the way up to the current understanding of the science behind this distressing disease. Travelling all over the world he talks to the people at the cutting edge in laboratories about the latest avenues of research as they race to find a cure. He takes time to talk to sufferers and their families gaining a heartfelt understanding of the anguish they go through every day. It is a clear and well-written exploration of the different efforts that encompass research into Alzheimer's. There is a small amount on Sir Terry Pratchett, who was sadly one of those to get early onset Alzheimer's, or his embuggerance as he called it. He donated a fairly hefty sum of money to enable research, but more importantly, he spoke about his illness and spent time raising awareness of it. Jebelli writes about a difficult and personal subject in a way that brings clarity to the dark world that is Alzheimer's, I can highly recommend this book. 4.5 stars
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  • Amy Leigh
    January 1, 1970
    Fantastic book full of history on the disease and things we can hope for, like a cure. Having a grandmother who had Dementia through my late teen years I wound up babysitting her and reminding her who I was all too often. Now I have a future mother in law with it and she is very stubborn. My fiancé says I have helped them both so much but I hate witnessing what they both go through.This book gives you ideas for situations you may be in and an idea of progression- although everyone is different. Fantastic book full of history on the disease and things we can hope for, like a cure. Having a grandmother who had Dementia through my late teen years I wound up babysitting her and reminding her who I was all too often. Now I have a future mother in law with it and she is very stubborn. My fiancé says I have helped them both so much but I hate witnessing what they both go through.This book gives you ideas for situations you may be in and an idea of progression- although everyone is different. It also offers reasons for a cure. This disease to me is plain evil! You start grieving a loved one while they are still alive.Highly recommend if you are interested in the history of this disease or have a loved one with Alzheimer's. Won this book through Goodreads Giveaways and wanted (was not asked) to offer a fair and honest review.
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  • Natalie S
    January 1, 1970
    We are currently staring down the barrel of an epidemic with respect to the aging disorders Alzheimer’s and dementia. Human beings are living longer and these diseases have increased to the point where it will soon be our leading cause of death, overtaking things like cancer and heart disease. There are claims that one in three of us will develop Alzheimer’s and that one in two people will care for someone with it. These claims are confirmation that books like Joseph Jebelli’s In Pursuit of Memo We are currently staring down the barrel of an epidemic with respect to the aging disorders Alzheimer’s and dementia. Human beings are living longer and these diseases have increased to the point where it will soon be our leading cause of death, overtaking things like cancer and heart disease. There are claims that one in three of us will develop Alzheimer’s and that one in two people will care for someone with it. These claims are confirmation that books like Joseph Jebelli’s In Pursuit of Memory are an important part of the conversation and it’s one that should be required reading by all.To read the rest of this review please visit: http://magazine.100percentrock.com/re...
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  • Ben
    January 1, 1970
    I received this book through GoodReads' "First Reads" in exchange for a review.Firstly, there is a very important topic for me. My great grandmother had Alzheimer's, as well as numerous others that I've gotten to know throughout my lifetime. One of the biggest things I often think about, and worry about, is the loss of my 'brain' in a working capacity, the memories, how to function, how to think, how to rationalize, philosophize, etc. Ever since seeing my great grandmother decay, visiting her tw I received this book through GoodReads' "First Reads" in exchange for a review.Firstly, there is a very important topic for me. My great grandmother had Alzheimer's, as well as numerous others that I've gotten to know throughout my lifetime. One of the biggest things I often think about, and worry about, is the loss of my 'brain' in a working capacity, the memories, how to function, how to think, how to rationalize, philosophize, etc. Ever since seeing my great grandmother decay, visiting her two-three times a week at the home with my Grammy.... it's always been one of my biggest fears and concerns. So this book was definitely of great interest to me, an Joseph Jebelli does an amazing job of showing both the scientific and the emotional side of things. As a relative of a patient he sympathizes greatly with those he's interviewed and those involved in the patient side of things. There is just so much to this disease, more than just the common thought of 'lost memories'. This is definitely a disease that needs to be eradicated now... like yesterday... like thirty years ago now.Jebelli does a good job of explaining the scientific jargon without over-explaining and dumbing down, also without exaggerating the illness, and just spelling it out exactly as it is, in all of it's various forms. The writing style is simple, easy flowing, and personable. A definite recommend for anyone with any kind of interest in the disease.
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  • Christina Dudley
    January 1, 1970
    I found this book unputdownable, and I've read plenty of Alzheimer's and brain books. Jebelli writes engagingly and with sympathy, tracing the history of the disease's discovery, its certain and possible causes, and its possible avenues toward a cure. Although it's too late for my mother-in-law, it made me want alternately want to give her a blood transfusion from a young person, hit her with a round of cancer drugs, and prepare some curry dishes for her to eat. Who cares if the human trials wer I found this book unputdownable, and I've read plenty of Alzheimer's and brain books. Jebelli writes engagingly and with sympathy, tracing the history of the disease's discovery, its certain and possible causes, and its possible avenues toward a cure. Although it's too late for my mother-in-law, it made me want alternately want to give her a blood transfusion from a young person, hit her with a round of cancer drugs, and prepare some curry dishes for her to eat. Who cares if the human trials were nonexistent or inconclusive at this point--could it possibly hurt? And if, by 2050, 135 million people worldwide will be sufferers, I'm all for throwing the spaghetti at the wall to see what sticks. (Not that this book isn't full of lots of good, solid science.)A great read, and a hopeful one, too, if you don't think too hard about the 135 million people who will require 135 million caregivers.Thank you to the publisher for the opportunity to read this excellent book.
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  • Kerena
    January 1, 1970
    I received a copy of 'In Pursuit of Memory' as part of a Goodreads giveaway in return for an honest review and I was not let down! The book is beautifully written. Although there is a lot of scientific knowledge and research that Jebelli has searched to the ends of the world to collect, he entwines a very personal and hopelessly sad journey of Alzheimer's within the pages of the novel. It was absolutely thrilling and captivating to read. It is a shame that investment into research this disease h I received a copy of 'In Pursuit of Memory' as part of a Goodreads giveaway in return for an honest review and I was not let down! The book is beautifully written. Although there is a lot of scientific knowledge and research that Jebelli has searched to the ends of the world to collect, he entwines a very personal and hopelessly sad journey of Alzheimer's within the pages of the novel. It was absolutely thrilling and captivating to read. It is a shame that investment into research this disease has barely increased. I found the number of paths of research being walked to find sense of this disease was vast and extremely thought-provoking. It was also fascinating to discover the variety and types of Alzheimer's from early onset to visual Alzheimer's. If you haven't read a scientific book before this is such as good start to ease you in but you definitely get your mind blown by the intricacy of this disease.
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  • Snoakes
    January 1, 1970
    In this interesting and informative book Joseph Jebelli tells us the story of Alzheimer's. Starting with the history of the disease - how and when it was first described, he leads us through the history of its diagnosis and the discoveries of the different variants, research into genetics, prevention and potential treatments. Along the way he meets patients and their families, doctors and the scientists at the cutting edge of the research. Packed with information but also totally readable it's a In this interesting and informative book Joseph Jebelli tells us the story of Alzheimer's. Starting with the history of the disease - how and when it was first described, he leads us through the history of its diagnosis and the discoveries of the different variants, research into genetics, prevention and potential treatments. Along the way he meets patients and their families, doctors and the scientists at the cutting edge of the research. Packed with information but also totally readable it's a good example of a popular science book - you learn a lot along the way.If one thing comes across more than anything it's that Alzheimer's is a ticking time-bomb and this research is currently woefully underfunded. Hope is in sight though - most experts seem to agree there is a light at the end of a very long tunnel.I had a copy of this as a Goodreads giveaway.
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  • Anne Showering
    January 1, 1970
    This is a very good book. It's fairly scientific, but full of compassion and hope. A moving read, I can recommend it
  • Alan
    January 1, 1970
    I was pleased to have won this book in a Goodreads First Reads giveaway.A very interesting book! This is a subject that I am interested in, as my late mother had Alzhiemer's. Recommended.
  • Michelle Olms
    January 1, 1970
    Great book
  • Tony
    January 1, 1970
    Goodreads giveaway winner...Thank you!
  • Tfalcone
    January 1, 1970
    Thank you Net Galley for the free ARC. This book gives a good overview of the current understanding of Alzheimer's disease. Unfortunately, the cause seems to be as elusive as ever. In addition to amyloid and tau, genetic markers are on the suspect list as well as prions as well as environmental causes. The only hope we have is the development of treatments and medications.
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